On 30 November and 1 December 2023 in the city of Palermo, the final meeting of the transnational project and the multiplier events E5 – Final Conference of the Erasmus+ Cli-CCHE project (climate change, cities, community and equity in health) took place. On 30/11/2023, the final meeting of the project was held at the Institute of Translational Pharmacology (IFT) of the National Research Council (CNR), attended by all project partners (UNICAM, CNR IFT, CYI, UB, ISCT).The meeting took place with both in-person attendance and online streaming. On December 1, at the Sala Lanza of the Botanical Garden of the University of Palermo, the event Multiplier E5 – Final Conference took place. The project involved national and international experts, local authorities, public administration, universities, schools, local actors, and citizens. In the two-day international conference in Palermo CLiCCHE was presented, and the project results were evaluated and validated, in addition, project sustainability strategies and possible follow-up activities were evaluated. This conference helped to create networks of collaboration with multidisciplinary figures, promoted the involvement of citizens, and increased awareness of the risks of climate change that cities face.